Toxoplasma gondii infection is a common public health problem in humans and animals throughout the world. In this sense, the State of Alagoas may detect failure in the prevention, diagnosis and treatment of gestational and congenital toxoplasmosis, due to the increasing number of cases distributed throughout the state, according to the DATASUS platform. Thus, aiming to contribute with data that assist in the prevention of toxoplasmosis in the state of Alagoas, the aim of this study was to analyze the seroepidemiological aspects of Toxoplasma gondii infection in domestic felines by investigating the presence of IgG anti-T. gondii and spatial analysis of infection in the municipality of Maceió, Alagoas. To this end, 337 samples were collected, 113 samples from a private laboratory, and 224 samples from the municipality's Zoonosis Control Unit (UVZ). Sera from blood samples were subjected to an indirect immunofluorescence reaction to detect IgG anti-T. gondii from felines with a cutoff point of 1:16 at the Laboratory of Infectious Diseases of Domestic Animals (LDIC) at the Federal Rural University of Pernambuco (UFPE).  To analyze the results, a descriptive analysis was carried out, determining dispersion measures for absolute and relative frequencies. It was possible to observe that of the 337 samples obtained, 33.53% (113/337) were seropositive. In the private laboratory, 57.52% (65/113) of the samples were positive. Of the UCZ samples, 42.5% (48/113) were positive. Regarding sex, 55.75% (63/113) were males and 44.25% (50/113) were females. In the age variable, it was observed that 60.18% (68/113) were ≥2 and ≤4 years old and 39.82% (45/113) were ≥1 and <2 years old. The district with the highest frequency was district I with 31.85% (36/113) followed by districts II with 16.81% (19/113) and district VII with 12.38% (14/113). The high percentage of feline infection found in this study is consistent with the growing number of gestational and congenital toxoplasmosis in the state of Alagoas, with the data presented as important prevention tools for the municipality of Maceió.