Banca de DEFESA: JÉSSICA CARDOSO PESSOA DE OLIVEIRA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : JÉSSICA CARDOSO PESSOA DE OLIVEIRA
DATE: 23/02/2024
TIME: 08:30
LOCAL: https://meet.google.com/eea-kcec-mzb
TITLE:

Epidemiological aspects of Schistosomiasis and mollusc fauna in the state of Pernambuco

KEY WORDS:

Schistosomiasis mansoni; Schistosoma mansoni; Biomphalaria spp.; Public health; Health education.

PAGES: 120
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Medicina Veterinária Preventiva
SPECIALTY: Doenças Parasitárias de Animais
SUMMARY:

Schistosomiasis, is a parasitic disease caused by trematodes of the Schistosoma, affecting approximately 250 million people worldwide. In Brazil, Schistosoma mansoni is the etiological agent responsible for the condition, and its cycle is characterized by the involvement of humans as definitive hosts and molluscs of the genus Biomphalaria as intermediate hosts. Schistosomiasis represents a critical Public Health challenge in the country, being endemic in several areas, especially in the Northeast region. The aim of this study was: 1) to carry out a space-time analysis and evaluate the influence of epidemiological factors on the occurrence of Schistosomiasis in the Microregion of Garanhuns - Pernambuco; 2) identify water collections that pose a risk in the transmission of Schistosomiasis, evaluate aquatic malacofauna and infection in molluscs by Schistosoma mansoni; 3) to develop an educational mobile application about parasitic zoonoses. To this end, a retrospective analysis was conducted using secondary data from the Schistosomiasis Surveillance and Control Program's Information System (SISPCE) between 2009 and 2019, covering 11 municipalities in the Microregion of Garanhuns. The information was analyzed using descriptive statistics and utilized to generate a Sankey diagram. Furthermore, a logistic regression analysis with Poisson distribution was carried out to establish the impact of population, mean income per person, and number of health buildings on the occurrence of disease. Out of 277,351 fecal analyses, 2,5% (6.921/277.351) cases were diagnosed in all municipalities. Bom Conselho, Garanhuns, and Correntes had the highest number of cases. After conducting logistic regression, it was found that the occurrence of the disease was influenced by epidemiological factors, but the trends varied among the different municipalities. The malacological collections occurred between 2020 and 2022 in the rural community of Quilombo Castainho (Garanhuns). The collected molluscs were identified and examined using light exposure and PCR to detect the parasite's DNA. A total of 925 molluscs were collected, identified as Biomphalaria glabrata (711/925), Biomphalaria straminea (134/925) and Biomphalaria sp. (80/925). Only B. glabrata (8/711) was found positive for S. mansoni infection. In addition to the epidemiological study, a mobile application called Parasitour® was developed, available for Android/iOS, which contains the primary information on parasitic zoonoses in Brazil and a database of recently published manuscripts. The mobile application was developed in the JavaScript programming language using the React Native library. For the treatment and storage of data, two support systems designed in the Visual Studio Code editor were developed and based on the agile project management methodology. Ultimately, effective disease control must be based on the One Health approach with integrated measures focusing on environmental management, treatment of human patients, and health education. Health education is essential in disseminating accurate information, enabling people to care for their health, adopt healthy practices and improve their quality of life.

COMMITTEE MEMBERS:
Externa à Instituição - VANESSA SANTOS DE ARRUDA BARBOSA - UFCG
Presidente - RAFAEL ANTONIO DO NASCIMENTO RAMOS
Externa ao Programa - 1076653 - RENATA PIMENTEL BANDEIRA DE MELO - UFRPEExterna à Instituição - TATIENE ROSSANA MÓTA SILVA
Externo à Instituição - VICTOR FERNANDO SANTANA LIMA - UFS