Banca de DEFESA: GYL EVERSON DE SOUZA MACIEL

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : GYL EVERSON DE SOUZA MACIEL
DATE: 22/06/2022
TIME: 08:00
LOCAL: Meet na plataforma do Google
TITLE:

EFFECT OF PHYSICAL TRAINING ON CARDIOVASCULAR AND RENAL MORPHOPHYSIOLOGY, OXIDATIVE STRESS AND BEHAVIOR IN RATS SUBMITTED TO THE CHRONIC USE OF ANABOLIC STEROIDS.

KEY WORDS:

Anabolic steroids,

Side effects,

Bodybuilding Gyms,

Aggressive Behavior,

Oxidative stress.

PAGES: 80
BIG AREA: Ciências Biológicas
AREA: Fisiologia
SUBÁREA: Fisiologia de Órgãos e Sistemas
SPECIALTY: Fisiologia Endócrina
SUMMARY:

With each decade, stanozolol indiscriminate use has been increasing in gyms, because it promotes strength increase without extra weight gain, does not convert into estrogen, does not cause excess water retention, in addition to helping with fat loss while preserving mass. muscle. However, indiscriminate use and without medical prescription, can cause cardiovascular complications, liver dysfunction, kidney damage, psychiatric disorders, thyroid reduction and infertility. We aim to investigate the effects of stanozolol on systolic pressure, renal, hepatic and behavioral parameters in sedentary and trained rats, in addition to describing the profile of bodybuilders in Pernambuco who use steroids (ASA). Considering that the literature addresses only during physical activities. For that, 40 animals were selected, aged 90 days and divided into four groups: vehicle control group (n=5) that received saline solution, intramuscularly and the stanozolol control group (n=5) in which stanozolol was administered, control group trained group (n=5) received saline solution intramuscularly and trained swimming, trained stanozolol group (n=5) received intramuscular stanozolol and trained swimming. Stanozolol showed significant increases in arterial pressure and oxidative stress. In addition to promoting behavioral changes among rats that grew up together, resulting in increased aggressiveness during and after steroid use. 30.2% of the sample consisted of EAA users. The use of stanozolol compromises the cardiovascular, renal and hepatic systems and promotes an increase in aggressive behavior at high doses. Something that needs to be circumvented, given the negative impact on health, when not properly prescribed.

BANKING MEMBERS:
Presidente - 6382973 - ANISIO FRANCISCO SOARES
Interna - 380.982.884-04 - MARIA ADELIA BORSTELMANN DE OLIVEIRA - UFRPE
Externa ao Programa - 1299724 - ANNA MYRNA JAGUARIBE DE LIMA
Externa à Instituição - NATALIE EMANUELLE RIBEIRO RODRIGUES - UPE
Externo à Instituição - LEUCIO DUARTE VIEIRA FILHO - UFPE