Banca de QUALIFICAÇÃO: BRUNA SILVA DE OLIVEIRA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : BRUNA SILVA DE OLIVEIRA
DATE: 31/10/2025
TIME: 10:30
LOCAL: Sala de seminários do PPGMV
TITLE:

Cutaneous inflammatory infiltrate pattern in dogs with natural Leishmania infantum infection before and after marbofloxacin treatment

KEY WORDS:

Zoonotic diseases; canine reservoir; specific diseases; histopathological analysis; One Health.

PAGES: 74
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Medicina Veterinária Preventiva
SUMMARY:

Visceral leishmaniasis, caused by Leishmania infantum, is a zoonosis with worldwide distribution. In dogs, it presents systemic clinical manifestations that often include cutaneous alterations such as exfoliative dermatitis, alopecia, ulcerations, and intense dermal inflammatory infiltration. These skin lesions have epidemiological importance, as they harbor high parasitic loads and play a fundamental role in maintaining the disease transmission cycle.Therefore, this study aims to analyze the inflammatory infiltrate in the skin of dogs naturally infected by Leishmania infantum before and after treatment with marbofloxacin, in order to identify histopathological alterations related to tissue response and the possible reduction of cutaneous parasitism. Histological processing of the samples is still in progress. Nevertheless, a literature review was conducted on the prevalence of canine leishmaniasis in Brazil, covering studies published between 1963 and 2025. The search for articles was performed in the PubMed, SciELO, and LILACS databases. The review showed a wide variation in prevalence among Brazilian regions, with higher rates observed in the Northeast and Southeast, particularly in states such as Bahia, Pernambuco, and Minas Gerais. The most frequently employed diagnostic tests were DPP®, ELISA, IFAT, and PCR, with the DPP® + ELISA combination standing out as the reference protocol in the most recent studies. The data demonstrate the persistence and expansion of canine leishmaniasis in different areas of the country, reinforcing the epidemiological relevance of the dog as the main urban reservoir.

COMMITTEE MEMBERS:
Presidente - JOAQUIM EVENCIO NETO
Externo ao Programa - 1929164 - FRANCISCO DE ASSIS LEITE SOUZA - UFRPEExterno à Instituição - DANILLO DE SOUZA PIMENTEL - UFAL