Banca de QUALIFICAÇÃO: LETYCIA ALMEIDA LISBÔA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : LETYCIA ALMEIDA LISBÔA
DATE: 21/07/2025
TIME: 09:00
LOCAL: Sala o Google Meting
TITLE:

Therapeutic protocol for treatment of atopic dermatitis in dogs: development of mousse and shampoo containing different ratios of cbd: thc

KEY WORDS:

Dermatitis, atopy, cannabis, dogs, Emulsion

PAGES: 86
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Patologia Animal
SPECIALTY: Anatomia Patologia Animal
SUMMARY:

Atopic dermatitis (AD) is a chronic allergic and inflammatory skin disease that affects dogs and cats. It is considered a multifactorial disease resulting from the interaction of environmental and genetic factors, leading to alterations in the skin barrier and immune response in predisposed patients. Because it is a controllable but not curable disease, lifelong therapy is often unavoidable. Therefore, it is essential to find a treatment that reduces the incidence of side effects and thus improves the quality of life of these patients. An oily extract of Cannabis sp. with different CBD:THC ratios will be used to treat atopic dermatitis in dogs. To determine the best treatment protocol, 32 dogs will be divided into four groups (GI, corticosteroid therapy; GII, CBD 1%:THC 0%; GIII, CBD 0.5%:THC 0.5%; GIV, CBD 0.25%:THC 0.75%). The oil extracts will be prepared into an emulsion to prepare the therapeutic formulations. The skin of atopic dogs will be evaluated clinically, using thermography, skin moisture measurement, and excisional biopsies for histopathological analysis. These will assess skin thickness, epidermal behavior, and the cellular pattern involved in dermal inflammation. Blood samples will be analyzed for interleukins involved in the inflammatory process and indicators of oxidative stress will be determined. The results will be expressed as mean ± standard deviation, and graphs will be generated using computer programs, adopting a significance level of p<0.05.

COMMITTEE MEMBERS:
Presidente - VALDEMIRO AMARO DA SILVA JUNIOR
Interna - ANA LUCIA FIGUEIREDO PORTO
Interno - ANISIO FRANCISCO SOARES
Externo à Instituição - TÚLIO ALEXANDRE FREIRE DA SILVA