Banca de DEFESA: INGRID ANAHI MORGUENSTERN

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : INGRID ANAHI MORGUENSTERN
DATE: 28/04/2025
TIME: 14:00
LOCAL: Auditório de Caprinos do Departamento de Medicina Veterinària
TITLE:

USE OF GELATIN AND HYDROXYETHYLCELLULOSE HYDROGEL TO HELP HEALING OF UNILATERAL MASTECTOMY IN BITCHES

KEY WORDS:

Biopolímeros; cães; curativos; neoplasias cutâneas.

PAGES: 83
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
SPECIALTY: Clínica Cirúrgica Animal
SUMMARY:

Wound healing is a complex process that depends not only on the nature of the injury and the type of treatment used, but also on the individual's homeostatic balance. In female dogs, mammary tumors are common and are often associated with poor nutritional status, metabolic diseases, and advanced age. The aim of this study was to evaluate the effect of a hydrogel made with gelatin and hydroxyethylcellulose on the healing of female dogs with mammary tumors who underwent unilateral mastectomy. The experimental group consisted of 15 female dogs with breast cancer. After unilateral mastectomy, each wound was initially divided into two halves using a ruler. The gelatin and hydroxyethylcellulose hydrogel was applied to the cranial half (Treated Group), and the hydroxyethylcellulose hydrogel was applied to the caudal half (Control Group). The hydrogels were formulated, sterilized at 121°C for 15 minutes and microbiologically tested (BHI broth) in five batches, with negative results in all, ensuring the microbiological safety of the product. After surgery, the wounds were treated every 72 hours with 0.1% polyhexanide biguanide and the hydrogels (GT and GC) until the 7th post-surgical day. The sutures were removed on the 15th day, and at this same time a 6mm punch biopsy was performed in the middle third of each half, subsequently sending the obtained material for histopathological analysis. Based on the results achieved, it is concluded that the hydrogel based on gelatin and hydroxyethylcellulose did not present any difference in the healing process of unilateral mastectomies in female dogs, when compared to the GC, and it is suggested that further research be carried out, with a larger experimental group, aiming to evaluate the action of the gelatin and hydroxyethylcellulose hydrogel in the healing of postoperative wounds.

COMMITTEE MEMBERS:
Presidente - GRAZIELLE ANAHY DE SOUSA ALEIXO CAVALCANTI
Externa ao Programa - 2309518 - LILIAN SABRINA SILVESTRE DE ANDRADE - UFRPEExterno ao Programa - ***.476.384-** - ROBERIO SILVEIRA DE SIQUEIRA FILHO - UFRPE