Banca de DEFESA: MARIA CLARA CUNHA PARANHOS DE OLIVEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MARIA CLARA CUNHA PARANHOS DE OLIVEIRA
DATE: 20/02/2025
TIME: 14:00
LOCAL: Auditório Luis de Melo Amorim
TITLE:

PREVENTIVE MASTECTOMY AS A RISK-REDUCING SURGICAL STRATEGY FOR MAMMARY TUMORS IN FEMALE DOGS

KEY WORDS:

canine; lymphadenectomy; breast; ovariohysterectomy; prophylaxis.

PAGES: 73
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
SPECIALTY: Clínica Cirúrgica Animal
SUMMARY:

Canine mammary neoplasms are highly frequent in veterinary clinical-surgical routine, standing out as one of the most common tumors in female dogs. However, despite the wide frequency and histological diversity of mammary cancer, it is still necessary to conduct studies related to the best methods for preventing mammary tumors. The present research project aimed to perform unilateral mastectomy coupled with axillary and inguinal lymphadenectomy as the gold standard treatment in female dogs with mammary tumors in only one mammary chain, as well as to analyze the need for contralateral preventive mastectomy as a prophylactic treatment for the emergence of breast neoplasms in remaining mammary chains, through the evaluation of tumor recurrence in these patients with unilateral breast tumors, concomitantly analyzing epidemiological, preventive, pathophysiological, clinical, diagnostic and therapeutic aspects of breast tumors in female dogs. The experimental group consisted of 23 female dogs, aged 8 to 15 years, weighing 5 to 25 kg, of various breeds, with breast tumors restricted to a single mammary chain. They underwent additional exams for tumor staging and subsequent axillary and inguinal lymphadenectomy, unilateral mastectomy and ovariohysterectomy, in those dogs that were not spayed. All information regarding the patients was described and recorded in individual files, including data on: time of disease progression; postoperative healing on days 1 (D1), 7 (D7), 10 (D10) and 15 (D15), and were monitored for possible changes, including the presence of hyperemia, dehiscence, odor, exudation, hematoma, edema and coloration; period of remission after treatment; evidence of the presence of neoplasia in the remaining mammary chain; result of the histopathological examination; presence or absence of metastasis in lymph nodes and other organs and survival of the animals. The patients were followed for a period of 8 months to assess local and contralateral recurrence or possible distant metastasis. A total of 28 nodules were identified, with a prevalence of carcinoma as a malignant tumor and adenoma as benign. Only one patient presented radiographic signs suggestive of pulmonary metastasis, being the only one to present metastasis in lymph nodes. 3 presented recurrence in the contralateral chain, however, both were benign.

COMMITTEE MEMBERS:
Presidente - GRAZIELLE ANAHY DE SOUSA ALEIXO CAVALCANTI
Externa à Instituição - FLAVIA CORREA MAIA
Externo à Instituição - ROBERIO SILVEIRA DE SIQUEIRA FILHO - UFRPE