Banca de DEFESA: NAYADJALA TÁVITA ALVES DOS SANTOS

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : NAYADJALA TÁVITA ALVES DOS SANTOS
DATE: 07/06/2024
TIME: 14:00
LOCAL: Remoto - Google Meet - Link: meet.google.com/nxx-vpws-nag
TITLE:

HISTOPATHOLOGICAL ANALYSIS AND MOLECULAR DIAGNOSIS OF DISEASES TRANSMITTED BY TICKS IN DOMESTIC AND WILD ANIMALS IN PARAÍBA AND PERNAMBUCO

KEY WORDS:

tick. histopathology. molecular pathology. PCR. zoonoses

PAGES: 97
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Patologia Animal
SPECIALTY: Anatomia Patologia Animal
SUMMARY:

Tick-borne diseases (TBDs) are targets of constant research in human and veterinary medicine, most of the time they are neglected diseases in Latin America, being considered a group of frequent diseases, given the tropical and subtropical climate that favors the emergence of diseases. . Among these diseases, we have those caused by protozoa of the genus Babesia, Hepatozoon, and those caused by bacteria such as those of the genus Ehrlichia, Rickettsia, Anaplasma and Borrelia. The objective of this work was to diagnose, through molecular and histopathological means, diseases transmitted by ticks in domestic and wild animals in the states of Paraíba and Pernambuco. The study was carried out in the regions of Agreste and Litoral Paraibano and the Zona da Mata Pernambucana region, which are fragments of the Atlantic Forest. The retrospective study was carried out by surveying cases from the pathological diagnosis book from 2013 to 2020, as well as the prospective study, between the years 2021 and 2022. For histopathological evaluation, the organs that presented lesions and their histological location were described. Fresh blood samples or tissues fixed in formalin and embedded in paraffin had DNA extracted and subjected to Polymerase Chain Reaction (PCR). Detection/confirmation of tick-borne pathogens was assessed through amplification of specific genes using primer oligonucleotides previously described for the specific pathogen. For better understanding, this thesis was divided into a literature review and three chapters, they are: Chapter 1 “Diseases transmitted by ticks in small animals in Paraíba”; Chapter 2 “Diseases transmitted by ticks in production animals in Paraíba and Pernambuco”; and Chapter 3 “Tick-borne diseases in wild animals in Paraíba”. As a result, it is possible to diagnose diseases transmitted by ticks in domestic and wild animals in the states of Paraíba and Pernambuco, through histopathological examination and molecular means. Through diagnosis, it is possible to map collection sites for molecular diagnosis and characterize the species of pathogens that occur in scientific areas, as well as detect which of them are considered zoonotic and contribute to disease control and prevention programs within the single health system.

COMMITTEE MEMBERS:
Presidente - FRANCISCO DE ASSIS LEITE SOUZA
Externa à Instituição - JULIANA FORTES VILARINHO BRAGA - UFPI
Externo à Instituição - LUCIANO SANTOS DA FONSECA
Externa à Instituição - LUCILENE DOS SANTOS SILVA - UFPI
Externo à Instituição - RICARDO BARBOSA DE LUCENA - UFPB