Banca de QUALIFICAÇÃO: SAULO ROMERO FELIX GONCALVES

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : SAULO ROMERO FELIX GONCALVES
DATE: 24/05/2024
TIME: 09:00
LOCAL: Google Meet:https://meet.google.com/hkm-ftvu-pei
TITLE:

Intravascular Large T-cell Canine Lymphoma – Report of Two Cases

KEY WORDS:

Lymphoproliferative disorder, endothelium, immunohistochemistry, dog.

PAGES: 15
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Patologia Animal
SPECIALTY: Anatomia Patologia Animal
SUMMARY:

Intravascular lymphoma (IVL) is rare in domestic species and humans, characterized by intravascular proliferation of neoplastic cells, with the central nervous system being the most affected site. The objective was to report the anatomopathological and immunohistochemical findings of two dogs diagnosed with Large T-cell Intravascular Lymphoma (LIV). Two canines were necropsied, an Akita male aged 4 years, and a Rhodesian ridgeback female aged 10 years. Both presented neurological clinical signs characterized by ataxia, seizures, and difficulty in locomotion. Macroscopically, hepatomegaly, splenomegaly, and necrotizing encephalitis were observed. Microscopically, there was a predominance of large intravascular neoplastic lymphocytes, with positive immunohistochemical staining for CD3 and negative for CD20, confirming the diagnosis of T-cell IVL in both cases. Thus, considering the complexity of this type of neoplasm, it emphasizes the importance of an interdisciplinary approach among veterinarians, allowing it to be considered as a differential diagnosis for other central nervous system disorders.

COMMITTEE MEMBERS:
Externa à Instituição - LORENA GABRIELA ROCHA RIBEIRO - UFS
Externo à Instituição - ALLUANAN ADELSON DO NASCIMENTO SILVA - UFRPE
Externa à Instituição - RAQUEL ANNES FAGUNDES SILVA - UFRPE