Occurrence of Newcastle disease virus (NDV) in Latin America and phylogenetic characterization of strains of Pigeon Paramyxovirus type 1 (PPMV-1) in reservoir animals in northeastern Brazil
Synanthropic birds, Newcastle disease, phylogeny, poultry, wild birds, genotypes
Newcastle disease virus (NDV), also known as avian paramyxovirus 1 (APMV-1), is among the most important viruses that infect avian species worldwide. This virus poses a serious threat, especially to the poultry industry, with the potential to cause significant economic losses. Given its wide circulation in the world and the wide range of existing genotypes, there is a high risk of reintroduction of virulent strains in the Brazilian domestic poultry industry, making surveillance of wild and domestic birds in our country a crucial process to adequately respond to new outbreaks. . Thus, the objective of this work was to carry out an investigation of the records of the circulates genotypes of the VDN in Latin America (AL) and to determine the occurrence and phylogenetic characterization of APMV-1 strains in free-ranging pigeons in the state of Pernambuco, region Northeast of Brazil. In this work, we describe the characterization of the genome of a virulent strain of NDV isolated from pigeons (Columba livia) in the state of Pernambuco. The strain found belongs to genotype VI, class II. Considered a virulent strain for pigeons and after several passages through production birds (Gallus gallus domesticus) it can also become virulent. Furthermore, we noticed that the strains most commonly found in AL belong to genotypes I, V, VI, VII, XII and XVI, all belonging to class II. We also noticed a lack of information on viral and epidemiological diversity regarding APMV-1 in LA. This fact demonstrates the importance of identifying possible isolates with the potential to cause outbreaks in our country.